MedShr Blog: An Approach to Appraising Randomized Controlled Trials

Demystifying Statistics in Medicine: An Approach to Appraising Randomized Controlled Trials

Randomized controlled trials (RCT) allow scientists to test whether an intervention leads to an outcome of interest. The first clinical trial dates back to 1747 and was conducted by James Lind; although not with the rigor of today, Lind selected 12 participants ravaged with scurvy and allocated in pairs to 6 groups1. The first pair…